Key Largo is about 60 miles south of Miami but a world away. You could drive around Miami for hours looking for a good breakfast place - you'll find several as soon as you pass into Key Largo. It feels much more local than Miami. Key Largo to Key West is a 100 mile and two hour minimum ride. Despite never being a few yards from water the views from the road are not great due to the protective mangroves that grow along the waters edge. It's been a while since I've been to Key West, however, after spending a day in Key Largo a return trip is one the horizon.